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1981/08/30

Axon Laboratory AcuityXpress 1.0.0.26

Axon Laboratory AcuityXpress 1.0.0.26
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AcuityXpress software is designed for enterprise level
data mining of high content screening experiments.
AcuityXpress shares the MDCStore. database with
MetaXpress. for seamless integration of data
acquisition, image analysis and informatics.
Cell by cell results are automatically linked with the
images and analysis results, all of which are stored
in the same database.

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1981/08/28

Axon Laboratory GenePix Pro 6.0.1.09

Axon Laboratory GenePix Pro 6.0.1.09
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GenePix Pro is the complete standalone image analysis
software for microarrays, tissue arrays and cell arrays

Why Choose GenePix Pro?

GenePix Pro is the industry standard microarray image
analysis software because of its unique combination of
imaging and analysis tools, visualizations, automation
capabilities, performance and ease of use.

IMAGING TOOLS

Display
GenePix Pro displays each of up to four single
wavelength images in a different user configurable
color, then constructs color ratio images from any
three pairs of channels as specified by the user.
Four channel imaging can be used to analyze multiple
channels from the same scan, or multiple one or
two color images from different scans. Select colors
from a fully customizable color palette.

Zooming buttons, hot keys, a Navigation Map and an
efficient Windows implementation make it fast and easy
to move around large images.

Feature Finding
GenePix Pro uses a set of proprietary feature finding
algorithms to find circular, square or irregular
features. Every pixel in a region around the feature
is examined by a local alignment algorithm and
assigned to feature or background. Global alignment
algorithms determine the translation, rotation and
skew of blocks of features.

Measuring Tools
Use the Measuring Tools to make detailed calculations
from specific regions on your arrays. GenePix Pro
automatically calculates statistics and graphs the
pixel data in the drawn region. Draw lines, polylines,
and wide lines to generate an intensity profile graph
of the line. Draw rectangles, polygons, and ellipses
to generate a histogram of pixel intensities insid
the region. Use these tools to obtain quick
measurements and channel comparisons without gridding
or analysis.

Image Alignment
If your non Axon images have to be aligned before they
can be analyzed, you have a number of methods of
aligning them in GenePix Pro. Drag one image over
another, or let GenePix Pro find the optimal alignment
for you.

Barcode Reading
GenePix Pro automatically reads barcodes from images.
Barcodes can be included automatically in file names,
and are exported with extracted data.

ANALYSIS TOOLS

Background Subtraction
Choose your background subtraction method from a
number of local and global methods, or correct your
data based on negative controls. Local background
correction is recommended for most microarrays because
even small variations in the background signal can
affect ratio values. For arrays on which the spots are
too close together to calculate an accurate local
background, you can specify a single value to subtract
from all features, for each channel. If you have
negative controls on your microarray, use the nearest
negative control, the mean of the nearest n negative
controls, or the mean of all negative controls as the
background value. At any time you can visually rev
the local background region assigned to a feature.

The Feature Viewer
Use the Feature Viewer to get on the fly access to
individual feature data, without analyzing the entire
image. The Feature Viewer displays images and data for
all acquisition wavelengths, and the three
user specified ratios. Feature Indicators are draw
directly in the Feature Viewer to instantly evaluate
individual features on a large array without having to
zoom in on each one.

The Feature Pixel Plot
The Feature Pixel Plot provides additional detailed
information about individual features, including a
scatter plot comparing individual pixels in the
selected wavelength channels.

Advanced Quality Control Flagging
General Boolean queries allow you to flag or highlight
data based on user defined criteria. Complex criteria
can be defined based on any measurements from the
Results table. Features identified by the query can be
marked with quality flags (good, bad), highlig
for further evaluation, or used to calculate a
normalization factor. Queries can be saved for use on
other arrays. Speed through analysis by defining in
advance the criteria you need to identify and isolate
both good and poor data, or control features.

Find
Use the Find function to search for all features w
a given Name or ID from anywhere in the GenePix Pro
interface.

Extracting Data from Images
A single click of the Analyze button automatically
calculates up to 108 different measurements for each
feature and displays the data on the in a spreadsheet.

Normalization
Normalize data with linear, ratio based methods, on
normalization features, selected features or all
features. For advanced users, GenePix Pro provides
fully general Boolean searches to define normalization
features.

Web Integration
GenePix Pro is fully integrated with web accessible
databases. No longer is your data isolated, waiting to
be imported into a larger database or analysis
program. Create a list of your favorite s to choose
from, or store a preferred in each GenePix Array
List file. Point at a feature, select Go To Web, and
your default web browser opens the database and
automatically queries the database for information
about the selected substance name or ID.

As with all other GenePix Pro features, Go To Web is
fully scriptable, so you can construct a custom view
of the data in a Report and embed hyperlinks to your
favorite databases.

Automation
Using a simple series of checkboxes, you can specify
automation for any or all steps in the GenePix system
from scanning through analysis and file saving.
Scripting allows even greater flexibility for
customized automation.

Standard Data Formats
Axon Instruments GAL and GPR file formats are
standards in the microarray industry.

GenePix Array List (GAL) Files
Easily construct lists describing the position and
content of each spot on an array from plain text
files. Substance name and ID lists can be pasted
directly into the array settings file to create a
GenePix Array List (GAL) file. GAL files can also
created from a collection of microwell plate files
using the GenePix Array List Generator. Add as many
columns as you like to the GAL file to track any
sample information along with GenePix results. See the
GenePix File Formats page for instructions.

GenePix Results (GPR) Files
GenePix Pro analysis Results are displayed in thei
own spreadsheet. Quality and normalization flags
appear graphically in their own column for easy
identification. Sort, flag, review images, save or
export all from the Results tab. Save data directly to
Acuity microarray informatics software.

GenePix Pro calculates up to 108 different
measurements for each spot, including:

Number of feature and background pixels for each
feature at each scan wavelength

Mean, median, and sum of pixel intensities at each
scan wavelength, for both feature and background
pixels

Ratio of mean pixel intensities, and ratio of median
pixel intensities

Signal to noise ratio

Medians and means of pixel by pixel ratios

Regression ratios

Sum of mean feature pixel intensities, and sum of
median feature pixel intensities

Standard deviations of feature and background pixel
intensities

Several spot quality measurements such as percent
saturated pixels, feature and background coefficients
of variation, and feature circularity

For a complete list and description of GenePix Pro
measurements, see the GenePix Results format on the
GenePix File Formats page.

Export as MAGE ML
Export microarrays in MAGE ML format for upload to
web based databases such as ArrayExpress. A growing
number of jouals, such as Nature, are requiring that
microarray data is made available in MAGE ML format as
part of publication. GenePix Pro gives you the ability
to export data in this format, and includes on the fly
compression during export to minimize file sizes.

Export as PDF
Easily generate high quality documents in Portable
Document Format (PDF). As one of the most widely used
electronic document formats in the world today, PDF
files are compact enough to send as e mail
attachments, but they still retain the original
formatting and preserve the high resolution and
quality of images and graphs. Unlike HTML, PDF fil
are self contained within a single file and make
cataloging and archiving GenePix Reports remarkably
easy. PDF files are searchable and import easily into
publishing software packages such as Adobe Photoshop
or Illustrator. For more information, read our
Knowledge Base Article on exporting graphics in
GenePix Pro.

Operation with Non Axon Scanners
While GenePix Pro cannot acquire images from
third party scanners, it can analyze these images.
GenePix Pro reads standard unsigned 16 bit grayscale
TIFF images acquired from any scanner, aligns the
scanned channels, and analyzes data from them as if
they were acquired on a GenePix scanner.

VISUALIZATIONS

Histograms
The Histogram tab automatically graphs a histogram of
the distribution of pixel intensities at each scanned
wavelength. The Histogram tab is updated instantly as
the image view changes so you can balance the signal
output for each channel dynamically during scannin

Also generate histograms of any analysis column, so
that you can review ratio or intensity distributions.

Scatter Plots
View scatter plots of pixels in individual features,
Whereas the Feature Pixel Plot plots the pixel
intensities from a single spot, the Scatter Plot t
automatically plots any analysis measurements from
every spot on the array. Clicking on a point on the
Scatter Plot displays the associated feature in the
Feature Viewer. Instantly assess the precision of your
data using regression and standard deviation lines on
the Scatter Plot. Data points selected on the Scatter
Plot are automatically highlighted on the Image and
Results tabs (and vice versa.)

LAB BOOK

The GenePix Pro Lab Book logs all file events that
occur while GenePix Pro is running. It automatically
records all saving of images, results, settings, and
Array List files. It also functions as an archive of
images and Results files: clicking on an image or
results file name opens that file directly into
GenePix Pro.

REPORTS AND SCRIPTING

GenePix Reports give the user unprecedented access to
scanner control and microarray data, as well as an
extensive set of tools to manipulate and display d
GenePix Pro supports standard scripting languages such
as VBScript and JavaScript as well as any other
scripting languages supported by Inteet Explorer,
such as PerlScript and PythonScript. Extract data via
script, write custom analyses through ActiveX objects,
generate HTML reports: GenePix Pro scripting is
maximally flexible.

Ready to use Analysis Reports generate quality control
reports of individual features and whole arrays,
identify interesting features according to
user defined criteria, evaluate replicates, and more.
Hardware Diagnostic Reports streamline and log ongoing
scanner performance validation. Example Reports give
you the building blocks to create and customize your
own scripts including scanner automation, images,
tables, and graphs without a degree in programming!
All scripts are editable for even greater flexibility.

GenePix Pro online help includes an extensive
Scripting Tutorial, which takes users through a full
course in HTML, VBScript and GenePix Pro scripting.

PRINTING

Print images, histograms and scatter plots directly
from GenePix Pro. The user can specify printed header
information, page formatting, and the full range of
fonts.

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1981/08/25

BENTLEY AUTOPIPE 08.05.01.11

BENTLEY AUTOPIPE 08.05.01.11
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Bentley AutoPIPE is a native Windows program for
calculating piping code stresses, loads and deflections
under static and dynamic loading conditions. AutoPIPE
analyzes systems of any complexity; with special features
for buried pipeline analysis, wave loading, fluid
transients, FRP/GRP pipe, and pipe / structure
interaction.

AutoPIPE combines object oriented graphics technology
with advanced analytical capabilities not found in other
programs to provide a truly unique tool for piping
analysis and design.

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1981/08/23

BENTLEY AUTOPLANT STRUCTURAL 08.06.00.11

BENTLEY AUTOPLANT STRUCTURAL 08.06.00.11
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Design, documentation and analysis of structural systems,
including steel, concrete and timber

An intuitive user interface, powerful tools and a host of
standard components support structural engineers and
designers in the design and documentation of a wide range
of structural systems. The flexibility of Bentley
Structural allows you to use many inteational and
regional industry standards or easily customize and
expand these standards to meet the needs of your
practice.

Bentley Structural building information modeling (BIM)
methodology supports 2D/3D or analytical workflows. Fully
integrated physical modeling and analytical modeling
allows you to work in either view at any time, while all
changes are automatically synchronized between the two.
In addition, drawings are automatically generated using
industry standard representations of the structural
systems all of which are fully customizable to meet your
needs.

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1981/08/20

BENTLEY JPEG2000 Support for MicroStation 2.0

BENTLEY JPEG2000 Support for MicroStation 2.0
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JPEG 2000 File Format Support for MicroStation V8 2004 Edition
This update adds support for:
JPEG 2000 raster file format for MicroStation V8 Raster Manager.
Also included in this update is a new version or the ECW file format.
This update requires MicroStation version 08.01.02.15 or higher.
Once installed, Raster Manager will support the jp2, j2k, j2c, jpc,
jpx and jpf file extensions. If your JPEG 2000 file does not display one
of these extensions, simply use the "." filter. Raster Manager will
then auto detect the file format by reading the file header.
Please note that file formats cannot be uninstalled. This setup program
will not create any entry under .Add or Remove Programs..
bentley/

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1981/08/18

BENTLEY Microstation 8.05.02.35

BENTLEY Microstation 8.05.02.35
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MicroStation is Bentleys flagship product for the design, construction
and operation of the worlds infrastructure. MicroStation and
ProjectWise, Bentleys server line for AEC collaboration, form a robust
foundation for Bentleys comprehensive portfolio of software solutions.
MicroStation makes you more productive and your organization more
successful. And MicroStation is a standard for AEC projects worldwide:
Forty eight of the 50 U.S. state transportation departments have
standardized on MicroStation.
Market researcher Daratech, Inc. ranked Bentley the leading AEC software
vendor to plant owner operators, as well as the leading provider of
plant specific platforms and conceptual plant creation solutions to
EPC firms.
Most of Engineering News Record.s Top 150 Global Design Firms rely
primarily on Bentley software for their AEC projects.
MicroStation Extensions are specialized tools available to all users
that integrate with and expand MicroStations core technologies.
Discipline specific Extensions, like MicroStation GeoGraphics, enable
easy adoption of Bentleys vertical application solutions
bentley/en US/Products/MicroStation/

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1981/08/15

BENTLEY PROCESS AND INSTRUMENTATION 08.06.00.14

BENTLEY PROCESS AND INSTRUMENTATION 08.06.00.14
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Intelligent plant schematics and scaleable use of
exteal relational databases
Using AutoCAD with an exteal relational database
environment, Bentleys AutoPLANT PID creates intelligent
plant schematics. With it, engineers can lea more about
their plant design in a fraction of the time required to
study hundreds of layout drawings or 3D models.

This cost efficient application reduces the design and
documentation time for capturing process information for
system design and plant studies (such as HAZOP studies),
ensuring compliance to OSHA 1910 and ISO standards.
Through its scaleable design, AutoPLANT PID is suitable
for large, midsized and small engineering companies and
plant operators, providing a key tool for the lifecycle
design and documentation of process plants.

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1981/08/13

BitDefender Professional Plus 8.0.200

BitDefender Professional Plus 8.0.200
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BitDefender Professional Plus integrates antivirus, firewall and
antispam modules into one comprehensive security package, tailored
to meet the needs of home and corporate Inteet users worldwide.

Antivirus
The mission of the AntiVirus module is to ensure detection and
removal of all viruses in the wild. BitDefender Antivirus uses
robust scan engines, certified by ICSA Labs, Virus Bulletin,
Checkmark, Checkvir and TUV.

Firewall
The firewall module protects your data and your privacy by
filtering the incoming and outgoing traffic, controlling cookies,
blocking malicious scripts and "XXX dialer" type programs.

AntiSpam
Quite simply put, the BitDefender AntiSpam module deals with the
problem of spam, so you dont have to.

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1981/08/11

Borland InterBase 7.5.1

Borland InterBase 7.5.1
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borland/us/products/interbase/index

Designed for use in the absence of a database administrator or IT support,
InterBase is powerful enough to support mission critical applications, yet
compact enough to run on very modest systems. InterBase can be easily
transported by disk, CD, or even dial up download. And, unlike enterprise
databases that require expensive ecosystems of support and maintenance,
Borland InterBase requires virtually no maintenance.

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1981/08/08

Borland InterBase 7.5.1 for Linux

Borland InterBase 7.5.1 for Linux
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borland/us/products/interbase/index

Designed for use in the absence of a database administrator or IT support,
InterBase is powerful enough to support mission critical applications, yet
compact enough to run on very modest systems. InterBase can be easily
transported by disk, CD, or even dial up download. And, unlike enterprise
databases that require expensive ecosystems of support and maintenance,
Borland InterBase requires virtually no maintenance.

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1981/08/06

CAE PowerTools FEvis Publisher 1.1.0.11

CAE PowerTools FEvis Publisher 1.1.0.11
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FEvis makes it easy to communicate finite element results with
customers and colleagues and enables these audiences to view and
examine the results in a dynamic way.

What does it do?

With FEvis, you select specific results from your Finite Element
Analysis that you want to communicate. You can add views that
highlight noteworthy points in the results. But the model and results
arent static images. Your customers and colleagues can display these
selected results and manipulate the model by rotating, panning and
zooming the model dynamically. This enables them to evaluate and
assess the analysis results more effectively than static images or
animations in AVI files.

Features:

Supported FE model formats: NASTRAN (.dat, .nas), ABAQUS, FEMAP
Neutral (.neu), CAEPT Neutral. Coming soon: Algor, I deas, FEMsys

Supported FE results formats: FEMAP Neutral (.neu), FEMAP Binary
Results (.fno), NASTRAN OUTPUT2 (.op2), NASTRAN F06 (.f06), CAEPT
Neutral. Coming soon: Algor, I deas, FEMsys

Supported element types: 1d (rods, beams), 2d (quadtrilateral and
triangular plates), 3d (hexahedra, pentahedra, tetrahedra)

Display contour plots

Display deformed plots

Tu on/off components (elements grouped by property id)

Store views saves view, which result(s) are displayed, contour
on/off, deformed on/off

Create e FEresults packages FEvis Viewer and your data file in on
executable email to your colleagues! Very compact (i.e. 70000
node/35000 tet element model, and 10 results is 1 MB).

Copy image to clipboard

Print image to printer

Dynamic rotation, panning and zooming using OpenGL (hardware
acceleration helpful though not required)

Show standard views (front, back, etc).

Can be embedded in a document (i.e. Word, Excel)

Support for CAEproject share your results online with your team!

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1981/08/03

COMPUSOFT WINNER 6.1A1

COMPUSOFT WINNER 6.1A1
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Winner has complete integration of the graphic part and
the quotation part! An action in the quotation will
immediately be reflected in the plan drawing and vice
versa. This means that the quotation is always updated
showing the correct item lines and numbers.

Another reason why this integration is important is in
case of trouble. Many CAD programs links the graphic part
with a quotation part from another software supplier. You
can read here why this can be an unfortunate situation
for the end user.

A fully integrated program gives much higher
reliability/security for the kitchen dealer while working
out his projects (much less mistakes). Therefore the
manufacturer will also get a much more correct order.
This becomes even more critical with automatic transfers
of orders.

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1981/08/01

COSMIC ST7 Compiler IDEA and ZAP Sim 4.5b

COSMIC ST7 Compiler IDEA and ZAP Sim 4.5b
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Cosmic ST7 Cross Development Tools

Cosmics toolchain for the ST7 family is part of a complete
and uniform product line incorporating over 20 years of
innovative design and development. All Cosmic products
include one year of technical support and updates.

All Cosmic C Cross Compilers for Windows include IDEA
Cosmics own integrated development environment which is
preconfigured for the ST7 family of processors. IDEA is
designed specifically for developing embedded applications
with Cosmic compilers. IDEA integrates an editor, project
manager, graphical smart build/make facility, program
analyzer, link file generator, documentation manager and ZAP
debugger into one easy to use environment running under
Windows 98/NT/2000 and XP.
Click here for more information about IDEA.

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